MOTS-c 10mg Vial | Mitochondrial-Derived Peptide

MOTS-c supplied as 10 mg of lyophilised powder in a sealed vial. A 16-residue peptide, molecular weight approximately 2174.6 g/mol.

What makes MOTS-c unusual

Almost every peptide and protein in your body is encoded in nuclear DNA. MOTS-c is not. It is encoded within the mitochondrial genome, in an open reading frame inside the 12S ribosomal RNA region, and mitochondria carry their own small circular DNA separate from the nucleus.

That is genuinely interesting rather than a marketing point. It means the mitochondrion is not simply a power plant receiving instructions, but a source of signalling peptides in its own right. MOTS-c belongs to a small class described as mitochondrial-derived peptides, identified only in the last fifteen years.

The state of the evidence

Published work associates MOTS-c with AMPK signalling and metabolic regulation, largely in cell and rodent models. This is early science: the peptide class was described recently, the literature is small, and human data is very limited. It is stocked as a research tool for laboratories working in that area, not because the picture is settled.

Price per milligram

This vial is £26.99 for 10 mg, which is £2.70 per milligram. Comparing suppliers on price per milligram rather than headline price is the only like-for-like comparison, because vial strengths are not standardised across this market.

Does it come with a certificate of analysis?

Supplied with a batch-specific certificate of analysis stating the batch reference, identity confirmation, chromatographic purity against specification, and the analytical method used. Purity by reverse-phase HPLC with mass spectrometric identity confirmation, and the certificate names the laboratory that performed the work.

How is it reconstituted?

Allow the sealed vial to reach room temperature before breaking the seal, which prevents condensation drawing moisture into the cake. Add bacteriostatic water slowly down the inside wall rather than directly onto the powder, then swirl gently until clear. Do not shake: agitation shears peptide chains. The volume added sets the working concentration, so calculate it before opening anything.

Cold chain and UK dispatch

Held at −20 °C from arrival to dispatch and shipped insulated with a cold pack, tracked. Return the vial to cold storage on arrival. Short transit excursions do not compromise a sealed lyophilised vial.

Supplied strictly for laboratory research use only. Not for human or veterinary use, and not for diagnostic or therapeutic application. Purchasers must be 18 or over and are responsible for compliance with the rules applying to them.